| 摘要 |
PURPOSE: To provide an ameliorative agent having excellent bloodstream- ameliorative action and useful for amelioration of abnormal perception such as Raynaud's syndrome or cryesthesia, numbness or pain according to bloodstream disturbance by including a specific physiologically active substance extracted from infected tissue as an active component. CONSTITUTION: This ameliorative agent contains a physiologically active substance extracted from infected tissue and has following properties as an active component. Properties: amorphous hygroscopic powder of light-yellowish brown color; solubility: soluble to water, methanol and ethanol; absorption of ultraviolet part: UV max at 255-275nm; ninhydrin reaction: positive; phosphorus qualitative analysis: positive; pentose qualitative analysis: positive; chloride qualitative analysis: positive; contains nucleic acid bases; protein detecting reaction: negative. The physiologically active substance may be obtained by aseptically triturating infected tissue infected to virus, extracting with physiological saline water, etc., removing the tissue piece, removing protein, making it adsorbed to an adsorbent such as activated charcoal and eluting the adsorbed component. As the virus, virus belonging to family Poxviridae is preferable. |
