| 摘要 |
PCT No. PCT/GB92/01612 Sec. 371 Date Nov. 14, 1994 Sec. 102(e) Date Nov. 14, 1994 PCT Filed Sep. 3, 1992 PCT Pub. No. WO93/05040 PCT Pub. Date Mar. 18, 1993Compounds of formula (I), <IMAGE> (I) <IMAGE> (a) <IMAGE> (b) wherein L is N or CRc, wherein Rc is hydrogen, alkoxy, halo, alkyl or cyano; Q is NR1, CH2, O, or S; Ra is hydrogen, halo, alkyl, amino, nitro or alkoxy; Rb is hydrogen, halo, alkyl or alkoxy; R1 is hydrogen, alkyl, alkenyl, aralkyl, alkanoyl, or alkanoylalkyl; R2 is alkoxy; R3 is hydrogen, chloro or fluoro; R4 is hydrogen, alkyl, amino optionally substituted by alkyl, halo, hydroxy or alkoxy; R5 is hydrogen, halo, alkyl, alkoxy, nitro, amino or alkylthio; R6 is hydrogen, halo, alkyl, alkoxy or amino; n is 0, 1, 2, 3, or 4; p and m are independently 0, 1 or 2; and Rq is hydrogen or C1-6 are 5-HT4 receptor antagonists.
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