| 发明名称 |
Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase |
| 摘要 |
Compounds of the formula <IMAGE> are disclosed as possessing inhibitory activity against angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) and thus being useful as cardiovascular agents. Processes for preparing these compounds are also disclosed.
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| 申请公布号 |
US5552397(A) |
申请公布日期 |
1996.09.03 |
| 申请号 |
US19930160540 |
申请日期 |
1993.12.01 |
| 申请人 |
E. R. SQUIBB & SONS, INC. |
发明人 |
KARANEWSKY, DONALD S.;ROBL, JEFFREY A. |
| 分类号 |
A61K38/00;C07D211/76;C07D223/10;C07D223/16;C07D225/06;C07D267/14;C07D279/06;C07D281/06;C07D281/10;C07D471/04;C07D487/04;C07D513/04;C07K5/078;(IPC1-7):A61K31/55;C07D403/12;C07D403/14;C07D223/12 |
主分类号 |
A61K38/00 |
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