发明名称 |
Method of using an elicitor to increase production of metabolites in biological cells |
摘要 |
A method for culturing fungal and plant cells in a culture medium containing an elicitor to increase production of a metabolite produced by the cells. For example, tobacco leaves produce the metabolite nicotine and the nicotine is produced in significantly greater amounts when the tobacco is cultured in a elicitor-containing medium. The elicitor is an oxidized Bovine Serum Albumin (BSA), or a glycosylated BSA, or an oxidized lysozyme, or glycosylated lysozyme or azetidine-2-carboxylic acid. Further, metabolite production is increased 1000% over the production of the metabolite when an elicitor is not added during the culturing method.
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申请公布号 |
US5552307(A) |
申请公布日期 |
1996.09.03 |
申请号 |
US19940334794 |
申请日期 |
1994.11.04 |
申请人 |
BAR-ILAN UNIVERSITY;RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY |
发明人 |
KESSLER, BEZALEL;FRENKEL, CHAIM;FRENKEL, DAPHNA;KESSLER, ABRAHAM |
分类号 |
C12N5/00;C12P17/00;C12P33/00;(IPC1-7):C12N5/00;C12N5/02 |
主分类号 |
C12N5/00 |
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