| 发明名称 |
Recombinant cytomegalovirus vaccine |
| 摘要 |
The present invention provides a non-defective adenovirus recombinant expression system for the expression of the HCMV gB subunit, an immunogenic fragment of the gB subunit, and for the expression of non-structural immediate-early exon 4 proteins, said recombinant HCMV-expressing adenovirus being useful as a vaccine.
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| 申请公布号 |
US5552143(A) |
申请公布日期 |
1996.09.03 |
| 申请号 |
US19940349006 |
申请日期 |
1994.12.02 |
| 申请人 |
THE WISTAR INSTITUTE OF ANATOMY & BIOLOGY;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
PLOTKIN, STANLEY A.;RICCIARDI, ROBERT P.;GONCZOL, EWA;BERENCSI, KLARA;RANDO, ROBERT F. |
| 分类号 |
A61K39/00;C07K14/045;C12N15/861;(IPC1-7):A61K39/295;A61K39/245;A61K39/235 |
主分类号 |
A61K39/00 |
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