发明名称 Process for preparing polyethylene glycol derivatives and modified protein.
摘要 <p>High purity polyethylene glycol derivatives of formula (I) are useful as protein modifiers of interferons, t-PA, EGF, various hormones, etc. The thus modified protein has minimized antigenicity, prolonged plasma half life, or improved transfer to tissue. A novel process for preparing high purity polyethylene glycol derivatives is also disclosed.</p>
申请公布号 GR3019991(T3) 申请公布日期 1996.08.31
申请号 GR19960401366T 申请日期 1996.05.20
申请人 SUMITOMO PHARMACEUTICALS COMPANY, LIMITED;SEIKAGAKU CORPORATION 发明人 ONO, KEIICHI;KAI, YOSHIYUKI;IKEDA, YOSHIHARU;MAEDA, HIROO;SAKURAI, KATSUKIYO;TANAKA, YOSHIKATSU;KUBOTA, MICHIO;KASHIMOTO, KAZUHISA
分类号 A61K38/00;A61K47/48;C07D251/26;C07K1/107;C08G65/32;C08G65/329;C08G65/333;C12N9/96;(IPC1-7):C08G65/32;C07K1/00 主分类号 A61K38/00
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