发明名称 |
Process for preparing polyethylene glycol derivatives and modified protein. |
摘要 |
<p>High purity polyethylene glycol derivatives of formula (I) are useful as protein modifiers of interferons, t-PA, EGF, various hormones, etc. The thus modified protein has minimized antigenicity, prolonged plasma half life, or improved transfer to tissue. A novel process for preparing high purity polyethylene glycol derivatives is also disclosed.</p> |
申请公布号 |
GR3019991(T3) |
申请公布日期 |
1996.08.31 |
申请号 |
GR19960401366T |
申请日期 |
1996.05.20 |
申请人 |
SUMITOMO PHARMACEUTICALS COMPANY, LIMITED;SEIKAGAKU CORPORATION |
发明人 |
ONO, KEIICHI;KAI, YOSHIYUKI;IKEDA, YOSHIHARU;MAEDA, HIROO;SAKURAI, KATSUKIYO;TANAKA, YOSHIKATSU;KUBOTA, MICHIO;KASHIMOTO, KAZUHISA |
分类号 |
A61K38/00;A61K47/48;C07D251/26;C07K1/107;C08G65/32;C08G65/329;C08G65/333;C12N9/96;(IPC1-7):C08G65/32;C07K1/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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