WATER-SOLUBLE PRESSURE-SENSITIVE MUCOADHESIVE

摘要

Water-soluble pressure-sensitive adhesives include a water-soluble polymer that is made tacky at room temperature by addition of a water-soluble plasticizer that is miscible with the polymer. Suitable polymers are solid at room temperature and have a hydrophilicity as measured by water uptake greater than about 25 %. Suitable plasticizers are liquid at room temperature and having a boiling point higher than about 80 DEG C. The adhesives according to the invention may conveniently be provided in dry film form. Preferred water-soluble pressure-sensitive adhesives of the invention adhere both to mucosal surfaces and to a variety of materials that may constitute a part of a device or prosthesis to be held in a body cavity that has a mucosal lining, and adhesive films of the invention are useful as denture adhesives. For use in the oral cavity preferred adhesives of the invention are made of GRAS- or NF-certified materials.