发明名称 |
STABLE HYDRATES OF A CEPHALOSPORIN CHLORIDE SALT |
摘要 |
The cephalosporin compound [6R, 7R]-7-[2-(2-amino-4-thiazolyl)-2-(Z)-(methoxyimino)acetamido]-3-[1-(methylamino)pyridinium-4-thiomethyl]-ceph-3-em-4-carboxylic acid chloride hydrochloride is provided as a mono-, di- or tri-hydrate. The hydrates are produced by treating an aqueous solution of the corresponding carboxylate with hydrogen chloride and have been found to possess unexpectedly superior stability properties over other forms of the compound. The hydrates may be used in the treatment and/or prevention of bacterial infections in humans and animals.
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申请公布号 |
WO9626209(A1) |
申请公布日期 |
1996.08.29 |
申请号 |
WO1996GB00373 |
申请日期 |
1996.02.19 |
申请人 |
PFIZER INC.;WEBSTER, RICHARD, ANDREW, BENTLEY |
发明人 |
WEBSTER, RICHARD, ANDREW, BENTLEY |
分类号 |
C07D501/04;A61K31/545;A61K31/546;A61P31/04;C07D501/00;C07D501/36;(IPC1-7):C07D501/36 |
主分类号 |
C07D501/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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