A METHOD FOR IDENTIFYING ANTI-PARASITIC COMPOUNDS

摘要

The present invention relates to the use of nematode "cyclophilin-like proteins (CLP)", in a method for identifying compounds capable of binding to and/or inhibiting the peptidyl-prolylcistransisomerase activity of these proteins. Such compounds may be further screened for their ability to inhibit nematode parasites which are not susceptible to the anti-parasitic effects of CsA.