发明名称 |
Novel retinoids |
摘要 |
<p>Novel nonatetraenoic acid derivatives of the formula <CHEM> wherein the dotted bond is optional and R1 and R2 are as defined in the specific ation selectively bind to retinoic acid X-receptors (RXR) have anti-acne acitvity and potentiate the activity of retinoids having RAR alpha activity.</p> |
申请公布号 |
EP0728742(A2) |
申请公布日期 |
1996.08.28 |
申请号 |
EP19960102137 |
申请日期 |
1996.02.14 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
KLAUS, MICHAEL;LOVEY, ALLEN JOHN;MOHR, PETER;ROSENBERGER, MICHAEL |
分类号 |
A61K31/07;A61K31/16;A61K31/20;A61K31/23;A61K31/38;A61K31/381;A61P3/02;A61P17/10;A61P35/00;A61P35/02;C07C47/45;C07C47/548;C07C59/64;C07C61/16;C07C63/00;C07C403/20;C07D211/70;C07D333/24;(IPC1-7):C07C403/20 |
主分类号 |
A61K31/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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