摘要 |
Compounds of the general formula (I) <IMAGE> (I) wherein R1represents a hydrogen, fluorine or chlorine atom or a methyl, C1-C3 alkoxy or nitro group; R3 represents a hydrogen atom or a C1-C3 alkyl group; R4 represents a 2,3-dihydro-1H-inden-2-yl, 2,3-dihydro-1H-inden-1-yl or 1,2,3,4-tetrahydronaphthalen-1-yl group; or alternatively R3 and R4 complete, with the nitrogen atom to which they are attached, a 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indol-2-yl, 1,2,3,4-tetrahydro-9H-pyrido[4,3-b]indol-3-yl, 4,5,6,7-tetrahydrothieno[2,3-c]pyrid-6-yl, 4,5,6,7-tetrahydrothieno[3,2-c]pyrid-6-yl or 2,3-dihydro-1H-isoindol-2-yl group; are useful for the treatment and prevention of cerebral disorders.
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申请人 |
SYNTHELABO |
发明人 |
GEORGE, PASCAL;FROST, JONATHAN;PASAU, PATRICK;ROUSSELLE, CORINNE;BARTSCH, R+E,ACU E+EE GINE;WILLIAMS, PAUL HOWARD;MULLER, JEAN CLAUDE |