发明名称 |
Phenylaminocarbonyl derivatives |
摘要 |
<IMAGE> (1) Compounds of formula (1) are described wherein Y represents a halogen atom or a group -OR1 where R1 represents an optionally substituted alkyl group; R2 represents an optionally substituted cycloalkyl, cycloalkenyl or polycycloalkyl group; R3 represents a hydrogen atom or an alkyl, aryl or aralkyl group; R4 represents an aryl or heteroaryl group; X represents -O-, -S-, -CH2- or -N(R5)-, where R5 is a hydrogen atom or an alkyl group; n is zero or an integer or value 1, 2 or 3; and the salts, solvates and hydrates thereof. The compounds are selective phosphodiesterase IV inhibitors and are useful for the prophylaxis or treatment of inflammatory diseases.
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申请公布号 |
US5550137(A) |
申请公布日期 |
1996.08.27 |
申请号 |
US19930077284 |
申请日期 |
1993.06.14 |
申请人 |
CELLTECH THERAPEUTICS LIMITED |
发明人 |
BEELEY, NIGEL R. A.;MILLICAN, THOMAS A. |
分类号 |
C07C233/29;C07C233/75;C07C235/46;C07C235/56;C07D213/75;C07D213/81;C07D239/42;(IPC1-7):A61K31/44;C07D213/30 |
主分类号 |
C07C233/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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