摘要 |
<p>A monoclonal antibody or fragment thereof, wherein at least the hypervariable region is from a monoclonal antibody having an affinity of at least 1011 l/mol, and at least the constant region (or, if no constant region, the variable region) is derived from human immunoglobulin. The high-affinity monoclonal is from sheep or another mammal that gives higher affinity than a rodent.</p> |