摘要 |
Compounds of the formula: <IMAGE> (I) in which R1 represents a hydrogen or halogen atom or a methyl or C1-C4 alkoxy group, R'1 represents a hydrogen or halogen atom, R''1 represents a hydrogen atom or a methoxy group, R3 represents a C1-C3 alkyl group, R4 represents a 2,3-dihydro-1H-inden-2-yl, 2,3-dihydro-1H-inden-1-yl or 1,2,3,4-tetrahydronaphthalen-1-yl group, or R3 and R4 together form, with the adjacent nitrogen atom, a 1,2,3,4-tetrahydroisoquinol-2-yl, 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinol-2-yl, 5,8-dimethoxy-1,2,3,4-tetrahydroisoquinol-2-yl, 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indol-2-yl, 1,2,3,4-tetrahydro-9H-pyrido[4,3-b]indol-3-yl, 4,5,6,7-tetrahydrothieno[2,3-c]pyrid-6-yl, 2,3-dihydro-1H-isoindol-2-yl or 2,3,4,5-tetra-hydro-1H-3-benzazepin-3-yl, group are useful in the treatment of cerebral disorders.
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申请人 |
SYNTHELABO |
发明人 |
FROST, JONATHAN;GEORGE, PASCAL;PASAU, PATRICK;BARTSCH, R+E,ACU E+EE GINE;ROUSSELLE, CORINNE;WILLIAMS, PAUL H.;MULLER, JEAN C. |