Verfahren zur Herstellung von L-Aspartyl-D-alanin-N-(thietan-3-yl)-amiden

摘要

The invention concerns a method of producing L-aspartyl-D-alanine-N-(thiethane-3-yl)-amides of general formula (I) by reacting D-alanine-thiethane amides of general formula (II) with oxazolidinone compounds of general formula (III) in an inert organic solvent, wherein R<1> stands for H or a selectively separable protective group, R<2>-R<5>, independently of one another, are identical or different and stand for H or linear or branched C1-C4-alkyl, and R<6> and R<7>, independently of each another, are identical or different and stand for H, linear or branched C1-C4-alkyl, aryl or a group which activates the carbonyl group.