| 发明名称 |
CAPL-SPECIFIC OLIGONUCLEOTIDES AND METHODS OF INHIBITING METASTATIC CANCER |
| 摘要 |
Disclosed are synthetic oligonucleotides, including ribozymes, having a nucleotide sequence complementary to CAPL nucleic acid. Also disclosed are methods of inhibiting the expression of CAPL gene and methods of inhibiting metastatic cancer using CAPL-specific oligonucleotides.
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| 申请公布号 |
WO9625499(A1) |
申请公布日期 |
1996.08.22 |
| 申请号 |
WO1996US02108 |
申请日期 |
1996.02.16 |
| 申请人 |
HYBRIDON, INC.;THE NORWEGIAN RADIUM HOSPITAL RESEARCH FOUNDATION |
发明人 |
FODSTAD, OYSTEIN;HOVIG, EIVIND;ENGEBRAATEN, OLAV;MAELANDSMO, GUNHILD;AGRAWAL, SUDHIR;VON HOFE, ERIC |
| 分类号 |
C12N15/09;A61K31/00;A61K31/70;A61K31/7088;A61K38/00;A61K48/00;A61P35/00;A61P35/04;C12N15/113;(IPC1-7):C12N15/52;C12N9/00;C12N15/11 |
主分类号 |
C12N15/09 |
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