| 发明名称 |
ADMINISTRATION OF A CYCLOSPORINE-SPECIFIC MONOCLONAL ANTIBODY THAT CROSS-REACTS WITH HIV-1 p24 GAG TO TREAT HIV INFECTION |
| 摘要 |
The generation of a monoclonal antibody that specifically recognizes N-methyl leucine residues (9 and 10) of cyclosporine is disclosed. This antibody also displays cross-reactivity towards the HIV-1 p24 Gag protein. Methods for the treatment of HIV infection and acquired immune deficiency syndrome employing this antibody are contemplated.
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| 申请公布号 |
WO9625175(A1) |
申请公布日期 |
1996.08.22 |
| 申请号 |
WO1996US02129 |
申请日期 |
1996.02.16 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF |
发明人 |
ERLANGER, BERNARD, F.;CHEN, BI-XING |
| 分类号 |
A61K38/00;A61K47/48;C07K7/64;C07K16/10;C07K16/14;C07K16/42;C07K16/44;C12P21/08;G01N33/68;G01N33/96;(IPC1-7):A61K39/42;C07K16/00 |
主分类号 |
A61K38/00 |
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