| 摘要 |
<p>Novel cephem derivatives represented by the general formula <CHEM> in which the Acyl substituent is a group of the formula <CHEM> wherein Ar is a lipophilic optionally substituted phenyl, naphthyl, pyridyl or benzthiazolyl group; R<1> is selected from certain optionally substituted aliphatic, aromatic, arylaliphatic or sugar moieties and R<2> and R<3> are each independently hydrogen, alkyl or aminoalkylcarbonylamino are gram-positive antibacterial agents, especially useful in the treatment of infectious diseases caused by methicillin-resistant Staphylococcus aureus (MRSA).</p> |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
KIM, CHOUNG U.;MISCO, PETER F.;WICHTOWSKI, JOHN A.;UEDA, YASUTSUGU;HUDYMA, THOMAS W.;MATISKELLA, JOHN D.;D'ANDREA, STANLEY W.;HOEFT, SHELLEY E.;MILLER, RAYMOND F.;MANSURI, MUZAMMIL M.;BRONSON, JOANNE J. |
