发明名称 Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates.
摘要 <p>Imidate derivatives of sulfamates having the following formula (I): &lt;CHEM&gt; wherein R1, R2, R3, R4 and X are as herein defined have been found to be useful prodrug and exhibit anticonvulsant activity when converted to the active agent upon administration to a mammal and are thus useful in the treatment of conditions such as epilepsy. Further, the present invention encompasses pharmaceutical compositions containing a compound of formula (I) as well as methods for their use.</p>
申请公布号 EP0574256(A1) 申请公布日期 1993.12.15
申请号 EP19930304497 申请日期 1993.06.10
申请人 MCNEILAB, INC. 发明人 MARYANOFF, BRUCE E.
分类号 A61K31/35;A61P25/08;A61P43/00;C07D493/14;C07D497/14;C07H9/04;C07H11/00;(IPC1-7):C07H9/04;A61K31/70 主分类号 A61K31/35
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