摘要 |
<p>Imidate derivatives of sulfamates having the following formula (I): <CHEM> wherein R1, R2, R3, R4 and X are as herein defined have been found to be useful prodrug and exhibit anticonvulsant activity when converted to the active agent upon administration to a mammal and are thus useful in the treatment of conditions such as epilepsy. Further, the present invention encompasses pharmaceutical compositions containing a compound of formula (I) as well as methods for their use.</p> |