| 摘要 |
2,9-disubstd. purin-6-ones of formula (I) and their tautomers and salts are new: R1 = 2-10C alkyl or phenyl(2-10C)alkyl opt. ring-substd. by halo, NO2, CN or 1-6C alkyl; R2 = H, OH, azido, 1-6C alkyl or OSO2R 5; R3 = H; or R2+R3 = O; R4 = H or 1-4C alkyl; R5 = 1-4C alkyl or phenyl; A = 3,4-methylenedioxyphenyl, 1-20C alkyl, 3-7C cycloalkyl, or phenyl (opt. substd. by 1-2 halo, CF3, COOH, NO2, CN, 1-5C alky, phenyl(1-5C)alkyl, 2-5C alkoxycarbonyl, phenyl(2-5C)alkoxycarbonyl, 1-5C alkoxy or phenyl(1-5C)alkoxy) and/or the rings are opt. substd. by phenyl or (1-5C)alkoxy phenyl. |
