| 摘要 |
PCT No. PCT/FR92/00404 Sec. 371 Date Aug. 22, 1994 Sec. 102(e) Date Aug. 22, 1994 PCT Filed May 4, 1992 PCT Pub. No. WO92/19583 PCT Pub. Date Nov. 12, 1992Aromatic bicyclic compounds of formula (I) CH2OH, -OH, -CHO, -CONH2, -COOH, -COOalkyl, -SH, S-alkyl, etc. . . . ; R2 is H; R3 is H, aryl, aralkyl or lower alkyl optionally substituted by a hydroxyl, a lower alkoxy or a -CO-R12, R12 being specifically H, lower alkyl, hydroxyl, lower alkoxy, or R2 and R3 together form a naphthalene ring with the benzene ring; R4 is a linear branched or unbranched alkyl having 1 to 15 carbon atoms or a cycloaliphatic radical; R5 represents specifically -(CH2)n-R13, -CH=CH-(CH2)n-R13, n being 0 or 1 to 6, R13 representing -COR15, monohydroxyalkyl, polyhydroxyalkyl, epoxy lower alkyl or -O-CO-R16, R15 representing specifically -OH, -Oalkyl, -Oaryl, R16 being specifically H, lower alkyl, aryl, or aralkyl; R6 and R7 are H, a halogen, lower alkyl or -OR16; and also the salts of the compounds of formula (I) in which R1 represents a carboxylic acid grouping; and the chiral analogues of the said compounds of formula (I).
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