发明名称 HETEROBICYCLIC COMPOUNDS
摘要 FIELD: organic chemistry. SUBSTANCE: product: compound of the formulawhere heteroatom X is oxygen but can be another one. Group W is preferably carbonyl-group but can have another values. Preferable heterocyclic ring is 4-oxo-4H-1-benzopyrane ring and it can have the broad spectrum of substituents R, R, Rand R. Y is the bound group taken from the broad spectrum but involving -COO-, -CONH-, -O-, -SO- and SONH-. Z is alkylene chain and B - complex amine. These compounds and their prodrugs, enantiomers and diastereomers, N-oxides and pharmaceutically acceptable salt can be used in medicine for treatment hypertension, in urology (benignity prostate hypertrophy) and other diseases. EFFECT: improved method of synthesis.
申请公布号 RU94043324(A) 申请公布日期 1996.08.20
申请号 RU19940043324 申请日期 1993.02.23
申请人 REKORDATI S.A.;KEMIKAL EHND FARMAS'JUTIKAL KOMPANI 发明人 LEONARDI AMEDEO;MOTTA DZHIANNI;RIVA KARIO;TESTA RODOL'FO
分类号 A61K31/352;A61P13/08;C07D307/79;C07D307/80;C07D311/22;C07D311/30;C07D311/32;C07D311/60;C07D335/06;C07D405/04;C07D405/12;C07D405/14;C07D407/04;C07D407/12;C07D409/04;C07F9/6558 主分类号 A61K31/352
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