摘要 |
FIELD: organic chemistry. SUBSTANCE: product: compound of the formulawhere heteroatom X is oxygen but can be another one. Group W is preferably carbonyl-group but can have another values. Preferable heterocyclic ring is 4-oxo-4H-1-benzopyrane ring and it can have the broad spectrum of substituents R, R, Rand R. Y is the bound group taken from the broad spectrum but involving -COO-, -CONH-, -O-, -SO- and SONH-. Z is alkylene chain and B - complex amine. These compounds and their prodrugs, enantiomers and diastereomers, N-oxides and pharmaceutically acceptable salt can be used in medicine for treatment hypertension, in urology (benignity prostate hypertrophy) and other diseases. EFFECT: improved method of synthesis. |