Process for producing 2-fluorocyclopropanecarboxylic acid
摘要
<p>A process for producing a 2-fluorocyclopropanecarboxylic acid of formula ÄIÜ <CHEM> wherein R is hydrogen or lower alkyl, comprises reducing a 2-halo-2-fluorocyclopropanecarboxylic acid of formula ÄIIÜ <CHEM> wherein R is as defined above and X is a halogen, by (i) developing a Raney nickel alloy in the presence of the 2-halo-2-fluorocyclopropanecarboxylic acid of formula ÄIIÜ, or (ii) by contacting the 2-halo-2-fluorocyclopropanecarboxylic acid of formula ÄIIÜ with hydrogen in an aqueous solvent in the presence of a Raney nickel catalyst.</p>
申请公布号
EP0726244(A1)
申请公布日期
1996.08.14
申请号
EP19960300680
申请日期
1996.01.31
申请人
SUMITOMO CHEMICAL COMPANY, LIMITED;DAIICHI PHARMACEUTICAL CO., LTD.