发明名称 Process for producing 2-fluorocyclopropanecarboxylic acid
摘要 <p>A process for producing a 2-fluorocyclopropanecarboxylic acid of formula ÄIÜ &lt;CHEM&gt; wherein R is hydrogen or lower alkyl, comprises reducing a 2-halo-2-fluorocyclopropanecarboxylic acid of formula ÄIIÜ &lt;CHEM&gt; wherein R is as defined above and X is a halogen, by (i) developing a Raney nickel alloy in the presence of the 2-halo-2-fluorocyclopropanecarboxylic acid of formula ÄIIÜ, or (ii) by contacting the 2-halo-2-fluorocyclopropanecarboxylic acid of formula ÄIIÜ with hydrogen in an aqueous solvent in the presence of a Raney nickel catalyst.</p>
申请公布号 EP0726244(A1) 申请公布日期 1996.08.14
申请号 EP19960300680 申请日期 1996.01.31
申请人 SUMITOMO CHEMICAL COMPANY, LIMITED;DAIICHI PHARMACEUTICAL CO., LTD. 发明人 ITAYA, NOBUSHIGE;WAKITA, RYUHEI;KUBO, ASAKO;SASAKI, MIKIO;NAMBA, TAKASHI;YUKIMOTO, YUSUKE
分类号 C07C51/377;C07C61/15;(IPC1-7):C07C51/347 主分类号 C07C51/377
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