发明名称 |
Production of antibodies from transgenic animals |
摘要 |
Chimaeric or wholly foreign immunoglobulin is obtained from cells or body fluid of a transgenic animal which has had inserted into its germline genetic material that encodes for at least part of an immunoglobulin, of foreign origin or that can rearrange to encode a repertoire of immunoglobulins, i.e. derived from a different animal source. For example, wholly human immunoglobulins may be produced from a transgenic mouse, possibly in response to an immunogen subsequently introduced to the mouse.
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申请公布号 |
US5545807(A) |
申请公布日期 |
1996.08.13 |
申请号 |
US19940286399 |
申请日期 |
1994.08.05 |
申请人 |
THE BABRAHAM INSTITUTE;MEDICAL RESEARCH COUNCIL |
发明人 |
SURANI, AZIM M.;NEUBERGER, MICHAEL S.;BRUGGEMANN, MARIANNE |
分类号 |
A01K67/027;A61K39/395;C07K1/00;C07K14/435;C07K16/00;C07K16/18;C07K16/46;C12N15/09;C12N15/85;C12P21/08;C12R1/91;(IPC1-7):C12N15/00;A61K39/00 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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