发明名称 |
Process for the preparation of diisopinocampheylchloroborane |
摘要 |
The present invention relates to an improved process for the in situ preparation of diisopinocampheylchloroborane which comprises reacting sodium borohydride and boron trichloride with alpha -pinene. The diisopinocampheylchloroborane thus obtained may be used, without isolation, to reduce prochiral ketones to their corresponding alcohols in high optical purity.
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申请公布号 |
US5545758(A) |
申请公布日期 |
1996.08.13 |
申请号 |
US19940289077 |
申请日期 |
1994.08.11 |
申请人 |
MERCK & CO., INC. |
发明人 |
KING, ANTHONY O.;LARSEN, ROBERT D.;VERHOEVEN, THOMAS R.;ZHAO, MANGZHU |
分类号 |
C07B41/02;C07B41/06;C07B53/00;C07D215/14;C07D215/18;C07D417/06;C07D495/04;C07F5/02;(IPC1-7):C07F5/02 |
主分类号 |
C07B41/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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