发明名称 |
MODIFIED GREEN FLUORESCENT PROTEINS |
摘要 |
Modifications in the sequence of Aequorea wild-type GFP provide products having markedly different excitation and emission spectra from corresponding products from wild-type GFP. In one class of modifications, the product derived from the modified GFP exhibits a n alteration in the ratio of two main excitation peaks observed with the product derived from wild-typ e GFP. In another class, the product derived from the modified GFP fluoresces at a shorter wavelength than the corresponding product from wild-type GFP. In yet another class of modifications, the product derived from the modified GFP exhibits only a single excitation peak and enhanced emission relative to the product derived from wild-type GFP.
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申请公布号 |
CA2343586(A1) |
申请公布日期 |
1996.08.08 |
申请号 |
CA19952343586 |
申请日期 |
1995.11.13 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
TSIEN, ROGER Y.;HEIM, ROGER |
分类号 |
C12N5/00;C12N15/12;C12N15/65;C12P21/02;G01N21/64;(IPC1-7):C12N15/12 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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