发明名称 |
MODIFIED LIGANDS FOR RECEPTOR TYROSINE KINASES |
摘要 |
The invention provides for synthetic ligands that bind to class I receptor tyrosine kinases. The ligands are analogous in structure to naturally occurring ligands. The modified ligands however, have eliminated the mid-sequence (B) domain present in the native ligands and replaced it with a peptide bridge which links the amino (A) and carboxy (C) domains. |
申请公布号 |
WO9623883(A2) |
申请公布日期 |
1996.08.08 |
申请号 |
WO1996US01465 |
申请日期 |
1996.02.02 |
申请人 |
BERLEX LABORATORIES, INC. |
发明人 |
HARKINS, RICHARD, N.;SETO, MARIAN;KATZ, BRADLEY, A. |
分类号 |
C12N15/09;A61K38/00;A61P35/00;A61P43/00;C07K14/495;C12N15/00;C12N15/12;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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