ANALOGS OF VITAMIN D, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION

摘要

FIELD: organic chemistry, vitamins. SUBSTANCE: invention relates to analogs of vitamin D of the general formula (I) where Y - sulfur atom; R is C1-C3-alkyl or R-C-R can form benzyl radical; Q is C2-C4-alkylene being one or more hydroxy-groups are protected as groups that can be converted to hydroxy-groups in vivo. These compounds show anti-inflammatory and immunomodulating effects and strong inducing activity with respect to differentiation and inhibition of nondesirable proliferation of definite cells. EFFECT: improved method of synthesis, valuable biological activities. 9 cl, 2 tbl, 38 ex