| 摘要 |
PURPOSE: To effectively and economically obtain a 3-substituted-3-methylbutanoic acid useful as an intermediate for perfumes, medicines, agrochemicals, etc., using an inexpensive and readily available raw material by oxidizing a butanol compound with oxygen in the presence of a specific catalyst. CONSTITUTION: (A) 3-Hydroxy-3-methylbutanol or 3-methyl-3-methoxybutanol is oxidized with oxygen in the presence of (B) water using (C) a platinum-based catalyst or a palladium-based catalyst to afford the objective 3-hydroxy-3- methylbutanoic acid or 3-methyl-3-methoxybutanoic acid. For example, the component (C) is prepared by supporting 1-10wt.% Pt or Pd and another metal such as Pb or Te on a carrier such as active carbon or alumina and used in an amount of 0.01-10wt.%, especially 1-5wt.% based on the reactional solution. The reaction is carried out at preferably 50-120 deg.C especially preferably 70-90 deg.C under preferably 1-30kg/cm<2> , especially preferably 1-10kg/cm<2> pressure in an oxygen gas atmosphere. |
