| 摘要 |
PURPOSE: To obtain a new low-molecular weight lipopolysaccharide, usable as a medicine and having ultrahigh safety and a high biological activity. CONSTITUTION: This new low-molecular weight lipopolysaccharide is obtained from a microbial cell and has physicochemical and biological properties of (a) 5,000±2,000 molecular weight measured by a sodium dodecyl sulfate- polyacrylamide get electrophoretic (SDS-PAGE) method using a protein marker without any recognizable stained band, (b) 1-3 molecules/5,000 molecular weight content of the hexosamine measured by the Elson-Morgan method, (c) 1-3 molecules/5,000 molecular weight content of the 2-keto-3-deoxyoctonate measured by a diphenylamine method and (d) at least 10EU/ng Limulus activity. |
