发明名称 Crystalline modification of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine, a method for the preparation thereof and a medicinal preparation based on it
摘要 PCT No. PCT/RU93/00018 Sec. 371 Date Nov. 17, 1994 Sec. 102(e) Date Nov. 17, 1994 PCT Filed Jan. 20, 1993 PCT Pub. No. WO94/17046 PCT Pub. Date Aug. 4, 1994A crystalline modification of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine prepared by cooling a solution of 2,4-dioxo-6-methyl-1,2,3,4-tetrahydropyrimidine in water, an organic solvent or in a mixture thereof with a cooling agent at a rate not below 6 DEG C./min to crystallization followed by separation of the obtained crystals and drying them. The crystalline modification has high antiinflammatory and wound-healing activity and is an active substance in medicaments used for treatment of burns and wounds of various organs.
申请公布号 US5543147(A) 申请公布日期 1996.08.06
申请号 US19940307654 申请日期 1994.11.17
申请人 LEONIDOV, NIKOLAI B. 发明人 LEONIDOV, NIKOLAI B.;SELEZENEV, NIKOLAI G.
分类号 A61K31/505;A61P27/02;C07D239/54;(IPC1-7):A61L15/16 主分类号 A61K31/505
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