COMPOUNDS AND METHODS FOR INHIBITING BETA -PROTEINCOMPOUNDS AND METHODS FOR INHIBITING BETA -PROTEIN FILAMENT FORMATION AND NEUROTOXICITY FILAMENT FORMATION AND NEUROTOXICITY

摘要

This invention relates to compounds and methods for inhibiting beta -protein filament formation and neurotoxicity, and more particularly to oligopeptides consisting of defined N-terminal amino acids from Alzheimer's beta -peptide (A beta ), such as the 2-9, 1-12 and 12-28 oligopeptides.