发明名称 |
PREPARATION OF OPTICALLY ACTIVE ALIPHATIC CARBOXYLIC ACIDS |
摘要 |
A process for the separation of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process comprises: (i) forming a diastereomeric salt by reaction comprising said racemic mixture of a C1 to C6 linear or branched aliphatic carboxylic acid and an amount of an Nalkyl-D-glucamine that is sufficient to react with one of the enantiomers of the racemic mixture; (ii) precipitating from the reaction solution formed in step (i) the diastereomeric salt; (iii) separating said precipitated diastereomeric salt; (iv) decomposing the salt into its enantiomeric component and its organic base component; and (v) isolating a substantially pure enantiomer from said decomposed salt.
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申请公布号 |
CA2211265(A1) |
申请公布日期 |
1996.08.01 |
申请号 |
CA19962211265 |
申请日期 |
1996.01.24 |
申请人 |
ALBEMARLE CORPORATION;ALBEMARLE CORPORATION |
发明人 |
PATIL, DEEPAK R.;RAMACHANDRAN, VENKATARAMAN |
分类号 |
C07B57/00;C07C51/487;C07C57/30;C07C57/58;C07C59/64;(IPC1-7):C07C215/10;C07C67/60;C07C69/612;C07C69/65;C07C213/10 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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