| 发明名称 |
THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY |
| 摘要 |
Compounds of formula (I) wherein R, R1, R2, R3, R4, <u>m</u> and <u>n</u> have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
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| 申请公布号 |
WO9622998(A1) |
申请公布日期 |
1996.08.01 |
| 申请号 |
WO1996EP00251 |
申请日期 |
1996.01.23 |
| 申请人 |
ZAMBON GROUP S.P.A.;PELLACINI, FRANCO;ROMAGNANO, STEFANO;NORCINI, GABRIELE;SANTANGELO, FRANCESCO |
发明人 |
PELLACINI, FRANCO;ROMAGNANO, STEFANO;NORCINI, GABRIELE;SANTANGELO, FRANCESCO |
| 分类号 |
C07D263/32;A61K31/42;A61K31/421;A61K38/55;A61P9/00;A61P9/08;A61P9/12;C07C319/20;C07C323/60;C07C327/32;C07D213/56;C07D261/08;C07D307/54;C07K5/06;(IPC1-7):C07K5/06 |
主分类号 |
C07D263/32 |
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