Methods and apparatus for external accumulation and photodissociation of ions prior to mass spectrometric analysis

摘要

The present invention discloses novel methods and apparatuses for mass spectrometry. In the methods and apparatuses of the invention, ions are accumulated in an ion reservoir and dissociated with coherent radiation prior to mass analysis. These methods and apparatuses are amenable to mass spectrometric analysis of biomolecules and are particularly usefuil for the sequencing of oligonucleotides, peptides and oligosaccharides.