Antifungal 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]triazolones and imidazolones

摘要

4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4 -yl]methoxy]pheny l ]-1-piperazinyl]phenyl]triazolones and imidazolones of formula wherein Q is CH or N; Y is a radical of formula R<1> is C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl; and R<2> is C1-6alkyl, C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl, the acid addition salts and stereoisomeric forms thereof; said compounds having antifungal properties. Pharmaceutical compositions containing such compounds as an active ingredient; methods of preparing said compounds and pharmaceutical compositions.