发明名称 |
Single-stranded labelled oligonucleotides of preselected sequence |
摘要 |
Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.
|
申请公布号 |
US5541313(A) |
申请公布日期 |
1996.07.30 |
申请号 |
US19940336500 |
申请日期 |
1994.11.09 |
申请人 |
MOLECULAR BIOSYSTEMS, INC. |
发明人 |
RUTH, JERRY L. |
分类号 |
C07H19/04;C07H21/00;C12Q1/68;(IPC1-7):C07H21/00 |
主分类号 |
C07H19/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|