摘要 |
PCT No. PCT/FR96/00575 Sec. 371 Date Oct. 16, 1997 Sec. 102(e) Date Oct. 16, 1997 PCT Filed Apr. 16, 1996 PCT Pub. No. WO96/33213 PCT Pub. Date Oct. 24, 1996A method for preparing streptogramins of the formula (I): <IMAGE> (I) wherein R1 is methyl or ethyl, R2 is H and X and Y together form an oxo radical, or R1 is ethyl, R2 and X are H and Y is H or OH, or else R1 is ethyl, R2 is OH and X and Y together form an oxo radical, by demethylation of a synergistin derivative of the formula (II): efined above, by means of a treatment with a periodate in an acetic medium, followed by a treatment in an aqueous medium. |