发明名称 |
2-{3-[4-(2-t-butyl-6-trifluoromethyl-4-pyrimidinyl)-1- piperazinyl] propylthio}-4-pyrimidinol fumarate |
摘要 |
The fumaric acid salt of 2-{3-[4-(2-t-butyl-6-trifluoromethyl-4-pyrimidinyl)-1-piperazinyl]propylthio}-4-pyrimidinol is useful for treating disorders which respond to dopamine D3 ligands. It has higher stability at low pH and is therefore particularly suitable for oral administration in pharmaceutical compositions comprising this salt.
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申请公布号 |
US6486162(B2) |
申请公布日期 |
2002.11.26 |
申请号 |
US20020039974 |
申请日期 |
2002.01.08 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
HOEGER THOMAS;STARCK DOROTHEA;TREIBER HANS-JORG;KOSER STEFAN;SCHAEFER BERND;THYES MARCO;BLANK STEFAN |
分类号 |
A61K31/506;C07D403/14;(IPC1-7):A61K31/506 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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