RECEPTOR SPECIFIC TRANSEPITHELIAL TRANSPORT OF IMMUNOGENS
摘要
Methods and products for modulating an immune response are provided. Pharmaceutical preparations contain a conjugate of an antigen and an FcRn binding partner. The conjugates are administered to mammals in effective amounts to modulate the immune system by stimulating the immune response against the antigen or tolerizing the immune system to the antigen. The antigen may be characteristic of a pathogen, of an autoimmune disease, of an allergen or of a tumor.
申请公布号
WO9622024(A1)
申请公布日期
1996.07.25
申请号
WO1996US00597
申请日期
1996.01.17
申请人
BRIGHAM AND WOMEN'S HOSPITAL, INC.;BRANDEIS UNIVERSITY
发明人
BLUMBERG, RICHARD, S.;SIMISTER, NEIL, E.;LENCER, WAYNE, I.