| 摘要 |
<p>A system and method for simulating the operation of biochemical networks includes a computer (100) having memory (106) used to store a set of objects (150) representing biochemical mechanisms with one or more associated signals (112) representing quantities or concentrations of associated proteins, positions of associated molecules, or other state information of the network, a set of methods for determining reaction probabilities for biochemical reactions associated with the objects and for simulating performance of those biochemical reactions, and output data (114) representing values of selected ones of the signals. The operation of the biochemical network is simulated for a specified simulation time period by executing at least a subset of the probability determination methods, selecting ones of the reaction simulation methods in accordance with the determined reaction probabilities, and executing the selected reaction simulation methods whereby associated ones of the signals are updated.</p> |
