摘要 |
<p>The present invention provides methods for inhibiting bone loss comprising administering to a mammal in need of treatment of a bone loss inhibiting amount of a compound of formula I
<Chemistry id="chema01" num="0001"><Image id="ia01" he="65" wi="85" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
wherein
R is hydrogen or methyl;
R<Sup>1</Sup> and R<Sup>2</Sup> each are methyl or ethyl, or R<Sup>1</Sup> and R<Sup>2</Sup> together with the nitrogen atom to which they are attached represent a saturated heterocyclic group; and
X is bromo, chloro, fluoro, or hydrogen; or a pharmaceutically acceptable salt thereof and, optionally, estrogen.</p> |