发明名称 |
Use of 13c-nmr to detect binding |
摘要 |
Methods of detecting binding of a putative ligand to a 13C-enriched target molecule, methods of screening for compounds which bind to a 13C-enriched target molecule, methods for calculating the dissociation constant of a ligand compound which binds to a 13C-enriched target molecule, and methods employed in the determination of the specific amino acids in a 13C-enriched target molecule affected by the binding of a ligand, as well as compounds identified by these screening methods, are provided herewith. |
申请公布号 |
HK1044817(A1) |
申请公布日期 |
2006.12.22 |
申请号 |
HK20020104719 |
申请日期 |
2002.06.25 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
FESIK, STEPHEN, W.;HAJDUK, PHILIP, J. |
分类号 |
G01N;G01N24/12;B08B9/04;C07B;C07K1/13;E21B37/04;G01N33/483;G01N33/50;G01N33/53;G01N33/542;G01N33/566;G01N33/68;G01N33/94;G01R33/46;G01R33/465 |
主分类号 |
G01N |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|