A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.
申请公布号
US5539082(A)
申请公布日期
1996.07.23
申请号
US19930054363
申请日期
1993.04.26
申请人
NIELSEN, PETER E.;BUCHARDT, OLE;EGHOLM, MICHAEL;BERG, ROLF H.
发明人
NIELSEN, PETER E.;BUCHARDT, OLE;EGHOLM, MICHAEL;BERG, ROLF H.