发明名称 2,3-DISUBSTITUTED ISOXAZOLIDINES, A PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE
摘要 The invention relates to compounds of the formula <IMG> (I) in which A denotes an optionally substituted radical from the series comprising alkyl, acyl, cycloalkyl, aryl and heteroaryl; B represents CO, CS, C=NH, CN-alkyl, CN-O-alkyl, SO, optionally substituted CH2 or a bond; D represents NH, NCH3, O, CH2 or a bond; E represents CHOH, CO, SO or optionally N-substituted C=NH; F represents O, NH, NCH3 or a bond; R4 denotes an optionally substituted radical from the series comprising alkyl, cycloalkyl, aryl and heteroaryl; and R8 denotes hydrogen or optionally substituted alkyl, to a process for their preparation, and to their use as inhibitors of prolyl hydroxylase.
申请公布号 CA1338484(C) 申请公布日期 1996.07.23
申请号 CA19870554535 申请日期 1987.12.16
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 HENKE, STEPHAN;BROCKS, DIETRICH;GUENZLER, VOLKMAR
分类号 C07D261/02;A61K31/42;A61K38/00;A61P1/16;A61P9/10;A61P11/00;A61P17/00;A61P43/00;C07K5/08;C07K5/083;C07K5/087;C07K5/09;C07K5/093;C07K5/097;(IPC1-7):C07K5/04;A61K38/04;A61K31/535 主分类号 C07D261/02
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