摘要 |
A difluoroprostacyclin of the following formula (V), its lower alkanol ester or its pharmaceutically acceptable salt: <IMAGE> (V) wherein A is an ethylene group, a vinylene group or an ethynylene group, R is a substituted or unsubstituted C1-10 alkyl group, a substituted or unsubstituted C1-10 alkenyl group, a substituted or unsubstituted C1-10 alkynyl group, a substituted or unsubstituted C3-8 cycloalkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryloxy group, Q is a substituted or unsubstituted C1-10 alkyl group, a substituted or unsubstituted C1-10 alkenyl group, a substituted or unsubstituted C1-10 alkynyl group, a substituted or unsubstituted C3-8 cycloalkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group.
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