| 摘要 |
Di-heterocyclyl-substd. heterocyclic cpds. of formula (I) and their salts, enantiomers or diastereomers, and derivs. with amino and amidino partly or completely protected, are new. X = O, S, NH or NA; Y = aziridino, azetidino, pyrrolidino, piperidino, hexahydroazepino or piperazine, each substd. by R2; R1 = a gp. of formula (a) or (b); R2 = CrH2rCOOR3; R3 = H, A or Ar; A = 1-6C alkyl; B = H, A, 3-7C cycloalkyl, CkH2kAr or amidino; Ar = phenyl or benzyl (both opt. substd. by 1 or 2 of A, Cl, Br, I, NO2, CN, OH, OA, NH2, NHA or NA2); k = 1-4; m, r = 0-4; and n = 2-4. |
