CARBOXAMIDES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF

摘要

FIELD: medicine. SUBSTANCE: new carboxamides of formula:wherein A, E, G, L, M, R and Q are as defined in the specification and also hydrates or solvates thereof, inhibit thrombin-induced accumulation of throbicides, and coagulation of fibrinogen in blood serum. Said agents can be prepared from the corresponding acid and the corresponding amine of formula: HNCHQ.. EFFECT: improved properties of the title compounds.