| 摘要 |
FIELD: organic chemistry. SUBSTANCE: invention relates to cephalosporin compound of formula (I):or pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate or isomers thereof, wherein Ris hydrogen or amino protecting group; Rand Rcan be the same or different and represent independently hydrogen or hydroxy protecting group, or Rand Rtogether form cyclic diol protecting group; Ris hydrogen or carboxy protecting group; R, Rand Rrepresent independently hydrogen, amino or substituted amine, hydroxy, alkoxy, C-alkyl, carboxyl or alkoxycarbonyl; or Rand Rtogether with carbon atoms to which they are attached form C-cycle, and Q represents CH or N, and to process for preparation thereof and to drug containing compound I as active ingredient. EFFECT: more efficient preparation process. |
