A human deoxycytidine kinase 2 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of malignancies and viral infections. Antagonist against such polypeptides and their use as a therapeutic to treat immunodeficiency disorders are also disclosed. Diagnostic assays for detecting diseases related to mutations in the hdCK2 nucleic acid sequence and the concentration of the polypeptide encoded by such nucleic acid sequence is also disclosed.
申请公布号
WO9621724(A1)
申请公布日期
1996.07.18
申请号
WO1995US00532
申请日期
1995.01.13
申请人
HUMAN GENOME SCIENCES, INC.;WEI, YING-FEI;KIRKNESS, EWEN, F.